Positron emission tomography (PET) is a diagnostic
imaging technique of nuclear medicine that is used
preferentially for clinical purposes in oncology,
cardiology and neurology.
It
is a a non-invasive method through
which functional images are taken after the administration to
the patient of specific radiopharmaceuticals that comprise molecules
(sugars, amino acids, metabolic precursors, hormones, etc) marked
with positron emission radioactive isotopes.
The aim of this technique is to study biological
functions like the metabolic activity, blood flow,
cell viability, cell proliferation, the transport of amino acids,
the density and occupation of neuro-receptors, etc.
This technique has a high capacity to distinguish
benignancy from malignancy in primary lesions, it can establish
the extension and scope of a malign tumor (staging), the detection
of recidivations and the response to treatment as well as the
diagnosis of diseases present without structural change that only
show biochemical changes, as is the case of psychiatric diseases.
Finally, it can identify the viable myocardic tissue and suitably
select the patients who could benefit from myocardic revascularization
procedures.
The equipment required for a PET exploration
comprises:
- PET Gamma camera: for the detection and
reproduction of the image after administration to the patient,
intravenously, of the radiopharmaceutical. The radionuclides
emit positrons during their passage through the organism (particles
with positive charge) that collide with negatively charged particles,
giving rise to two high-energy photons in opposing directions
(180º angle). The positron camera detects these two photons
simultaneously (detection by coincidence) to create images that
we visualize in the tomograph.
- High-tech computer equipment: allows storage
of data, reconstruction of the image and its visualization.